As I re-read the original strips from Life In Four Panels I realized I have a long history of mashing up music. Mostly listening to it. I did do some experiments with layering vocal tracks on instrumentals in college – kind of a proto-mashup I guess. That reminds me of one time a co-host on a show with me cut between the Prince and the Age of Chance versions of Kiss on air. I still have a recording of that somewhere.
I also made a lot of comics about mashups. The Grey Album was a pretty big deal when it came out – maybe the first mashup to feel get mainstream attention? Anyhow the comic below about the Gray Album doesn’t really fit anywhere anymore so I’m dropping it here.